Cleveland Clinic, IBM pioneered quantum computing in healthcare

Cleveland Clinic Global Health System and IBM have begun deployment of an IBM Quantum system, to be located at the Cleveland Clinic main campus in Cleveland.

The first quantum health computer, expected to be completed in early 2023, is a key part of the two organizations’ 10-year partnership to fundamentally advance the pace of biomedical research through high-performance computing. Announced in 2021, the Cleveland Clinic-IBM Discovery Accelerator is a joint center that leverages the medical expertise of the Cleveland Clinic with the technology expertise of IBM.

“The current pace of scientific discovery is unacceptably slow, while our research needs are growing exponentially,” says Dr. Lara Jehi, research information manager at the Cleveland Clinic. “We cannot afford to continue to spend a decade or more moving from a research idea in the lab to therapies in the market. Quantum offers a future to transform this pace, especially in drug discovery and machine learning.

Dr. Ruoyi Zhou, director of the IBM Research/Cleveland Clinic partnership, comments: “A sea change in the way we solve scientific problems is on the horizon. At IBM, we are more motivated than ever to co-create with the Cleveland Clinic and other sustainable discovery communities and harness the power of quantum computing, AI and hybrid cloud to usher in a new era of accelerated discovery in health care and life sciences.

Cleveland Clinic’s Discovery Accelerator leverages a variety of IBM edge computing technologies, including:

  • Generative Toolkit for Scientific Discovery and other generative modeling capabilities that leverage AI to infer knowledge gaps and generate hypotheses, and ultimately aim to accelerate the research process in the discovery of therapies and biomarkers;
  • RXN, a cloud-based platform that combines AI models and the ability to directly control robotic labs to enable end-to-end design and synthesis of novel chemical compounds;
  • Deep Search, a next-generation artificial intelligence tool for generating insights from large amounts of structured and unstructured technical documentation; and
  • High-performance hybrid cloud technologies that allow researchers to “burst” their workloads into the cloud and access the resources they need at scale.

The Discovery Accelerator also serves as the technology base for the Cleveland Clinic’s Global Center for Pathogen and Human Health Research, part of the Cleveland Innovation District. The center, supported by a $500 million investment from the State of Ohio, Jobs Ohio and the Cleveland Clinic, brings together a team focused on studying, preparing for and protecting against emerging pathogens and virus-related illnesses.

Through Discovery Accelerator, researchers leverage advanced computing technology to accelerate critical research into treatments and vaccines.

Together, the teams have already started several collaborative projects that benefit from the new computing power. Discovery Accelerator projects include a research study developing a quantum computing method to screen and optimize drugs targeted at specific proteins; improving a model for predicting cardiovascular risk following non-cardiac surgery; and the use of artificial intelligence to search the results of genome sequencing and large databases of drug targets to find effective, existing drugs that could help patients with Alzheimer’s disease and others. diseases.

A significant part of the collaboration is focused on educating tomorrow’s workforce and creating jobs to grow the economy. An innovative educational program has been designed for participants from high school to the professional level, offering training and certification programs in data science, machine learning and quantum computing to build the skilled workforce needed for research advanced computing of the future.

Featured photo: Drs. Lara Jehi and Ruoyi Zhou

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